Fachbereich 08: Biologie und Chemie - Master of Science - Bioinformatik und Systembiologie

Inhalte:
- Effiziente Algorithmen und Datenstrukturen aus verschiedenen Bereichen der Bioinformatik
- Verschiedene Bereiche des Algorithmendesigns, z.B. Optimalitätskriterien, Laufzeit, Mehrdeutigkeit, Tabellierung
- Systematische Trennung unterschiedlicher algorithmischer Aspekte wie Suchraum, Evaluation, Auswahl und deren effiziente Rekombination zur Lösung verschiedener bioinformatischer Probleme
- Neue Algorithmen und Anwendungen aus der aktuellen Forschung

Veranstaltung findet im SS2025 leider nicht statt.

The microbiome is the ecological community of commensal, symbiotic and pathogenic microorganisms found in and on all multicellular organisms from plants to animals. It includes bacteria, archaea, protists, fungi and viruses. The microbiome have been found to be crucial for immunologic, hormonal and metabolic homeostasis of its host, e.g. type 1 diabetes, Crohn’s disease, Parkinson’s, obesity, depression, …
This seminar shall cover step-by-step all necessary computation techniques to process and analyse a typical microbiome experiement. We focus on 16S rRNA amplicon data – sequences e.g. via Illumina – and analytical tools mostly from the Qiime2 platform. We start with sequence- and meta-data curation, proceed with OTU / ASV picking, diversity calculation, taxonomy assignment and interative data exploration before we advance to statistical testing, differential abundance-, correlation-, and co-occurence analysis.
Bring your own data (no prerequisite)! All presented techniques will be explored in interactive hands-on sessions. Depending on participants, this seminar might be taught in English.